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Description
This antibody was affinity purified using Semaphorin 6A (C-terminus) peptide (without carrier). The antibody detects a 120kDa protein corresponding to the apparent molecular mass of Sema-6A on SDS-PAGE immunoblots of Sema-6A transfected COS7 cells, human colorectal cancer cells, and rat PC12 cells. In addition, shRNA knockdown of Sema-6A expression significantly reduces detection of Sema-6A using anti-Sema-6A (C-terminus) antibody.
Immunogen
Semaphorin 6A synthetic peptide (coupled to carrier protein) corresponding to amino acids in the C-terminus of human Sema-6A. The sequence used is identical to similar regions in rat and mouse Sema-6A, and has low homology to other semaphorin family members.