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Description
This antibody was cross-adsorbed to a non-specific phospho-tyrosine peptide then affinity-purified using phospho-PLCγ1 (Tyr-775) peptide. The antibody detects a 150 kDa protein in human Jurkat and A431 cells treated with pervanadate, but is not observed in untreated cells.
Immunogen
PLCγ1 (Tyr-775) synthetic peptide (coupled to carrier protein) corresponding to amino acids around tyrosine 775 in human PLCγ1. This sequence has high homology to the conserved site in rat and mouse PLCγ1, and has low homology to PLCγ2.