Immunocytochemistry: 1:25, Immunofluorescence: 1:25, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1000
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Description
ATG16L1 Polyclonal Antibody. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The APG12-APG5-APG16L complex is esential for the elongation of autophagic isolation membranes. This complex initially associates in uniform distributio
Immunogen
n/a
Other Names
ATG16L1; APG16L; Autophagy-related protein 16-1; APG16-like 1