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Description
ATGL Polyclonal Antibody. Lipolytic enzymes are required for mobilization of fatty acids from triglyceride stores in adipose tissue. Energy homeostasis is affected by dysfunctional lipolysis and may contribute to the pathogenesis of obesity and insulin resistance. Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. It is now thought that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl-hydrola
Immunogen
n/a
Other Names
Adipose triglyceride lipase;ATGL;ATGL DESNUTRIN;Calcium independent phospholipase A2;Calcium-independent phospholipase A2;Desnutrin;FP17548;IPLA2 zeta;IPLA2-zeta;PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 2;Patatin-like phospholipase domain-containing protein 2;PEDF R;PHOSPHOLIPASE A2 CALCIUM INDEPENDENT ZETA;Pigment epithelium derived factor;Pigment epithelium-derived factor;plpl;plpl2;PLPL2_HUMAN;Pnpla2;Transport secretion protein 2;Transport secretion protein 2.2;Transport-secretion protein 2;Triglyceride hydrolase;TTS 2.2;TTS2;TTS2.2;ZETA;