Recombinant Human Aryl hydrocarbon receptor nuclear translocator (ARNT), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 54.8kDa. Partial: 1-474aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Class E basic helix-loop-helix protein 2; bHLHe2Dioxin receptor, nuclear translocatorHypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta