Purity >95% as determined by SDS-PAGE. Macrophage inflammatory protein-1 alpha (MIP-1-alpha), also known as CCL3, is a cytokine produced by macrophages. MIP-1-alpha binds the chemokine receptors CCR1, CCR4 and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1-alpha and MIP-1-beta heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).