If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Post-translational modification regulated by conjugation of a small ubiquitin-like modifier (SUMO) is involved in various cellular processes such as transcriptional regulation, apoptosis and nuclear transport. Recent proteomic analyses in mammalian cells revealed that a number of SUMO substrates and specific modifications by SUMO-1 are involved in essential processes, including chromatin organization, transcription, RNA metabolism, immunomodulation and development of the innate immune system.