bovine, canine, equine, guinea pig, human, mouse, rabbit, rat
Isotype
n/a
Format
purified
Size
100 μl
Concentration
n/a
Applications
Western Blot: 1.0 μg/mL
Reviews / Ratings
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Description
PEX12 Polyclonal Antibody. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.