Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000
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Description
ABCD1 Monoclonal Antibody (OTI4C2). ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. De
Immunogen
n/a
Other Names
ABCD1; ATP-binding cassette, sub-family D (ALD), member 1; ABC42; ALD; ALDP; AMN; adrenoleukodystrophy protein