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Description
ABCG5 Monoclonal Antibody (1B5E10). The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol ac
Immunogen
n/a
Other Names
ATP-binding cassette sub-family G member 5, ATP-binding cassette, sub-family G (WHITE), member 5, ATP-binding cassette, subfamily G, member 5, sterolin 1, sterolin-1, STSL