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Description
KIF7 Polyclonal Antibody. KIF7 encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Immunogen
n/a
Other Names
HLS2, ACLS, UNQ340, kinesin family member 7, JBTS12