A compound that stimulates the proliferation of pancreatic β cells rodent and human primary islets (ECmax = 200 and 400 nM, respectively, over four days); promotes β cell growth in vivo, increasing β cell mass and normalizing blood glucose in the RIP-DTA mouse model of β cell ablation
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
WS-6 β-cell proliferation pancreatic RIP-DTA IKKe EBP1 E2F transcription