Purity >98%. Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl-L-serine (ARA-S), have been isolated and characterized from bovine brain. During mass spectrometry lipidomics analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, was discovered. This novel class or compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels. N-arachidonoyl taurine, a prominent N-acyl taurine, activates both TRPV1 and TRPV4 with EC50 values of 28 and 21 μM, respectively.