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Description
Rat Anti-Mouse CD2/LFA-2-UNLB. Specificity: Mouse CD2/LFA-2 (Mr 45-58 kDa)CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules.^1 It is expressed on the surface of >95% of thymocytes, and essentially all B cells, T cells and NK cells. ^1-3 In the mouse, CD2 is the receptor for CD48.^4 CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, Tcell signaling and intra
1. Altevogt, P., U. Kohl, P. von Hoegen, E. Lang, and V. Schirrmacher. 1989. Eur. J. Immunol. 19:341-346. 2. Altevogt, P., M. Michaelis, and R.A. and B. A. Kyewski. 1989. Eur. J. Immunol. 19:1509. 3. Kato, K., M. Koyanagi, H. Okada, T. Takanashi, Y.W. Wong, A.F. Williams, K. Okumura, and H. Yagita. 1992. J. Exp. Med. 176:1241-1249. 4. Guckel, B., C. Berek, M. Lutz, P. Altevogt, V. Schirrmacher, and B.A. Kyewski. 1991. J. Exp. Med. 174:947. 5. Shaw, S., G.E.G. Luce, R. Quinones, R.E.