Purity > 90% as determined by SDS-PAGE. MW: 32.4kDa. Full Length of Mature Protein: 19-160aa. N-terminal 6xHis-SUMO-tagged. Mus musculus (Mouse). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS