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Description
Mouse Anti-ITGA2B Recombinant Antibody (Q90). This product is Mouse antibody that recognizes ITGA2B. The antibody Q90 can be used for immunoassay techniques such as: IHC, IHC-Fr, IHC-P, WB. This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.