Cerebral Dopamine Neurotrophic Factor (CDNF) (Active) protein
Description
CDNF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007, Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
Size
50 μg
Concentration
n/a
Applications
Cell Culture (CC),In vivo Studies (in vivo),SDS-PAGE (SDS),Western Blotting (WB)