An inhibitor of Hsp70 (IC50 = 0.5 μM) that is selective over Hsp90; binds the NBDs of Hsc70 (Ki = 10 μM) and Grp78 (KD = 80 nM); inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
biochemical heat shock protein inhibitor inhibit apoptosis cancer gene regulation signal transduction adenosine-derived Hsp70 Hsp 70 VER155008 VER 155088 VER155088