產(chǎn)品名稱 Ornithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric) from BIOVISION, INC.
    產(chǎn)品貨號 K176-100
    產(chǎn)品價格 現(xiàn)貨詢價，電話：010-67529703
    產(chǎn)品規(guī)格 100 assays
    產(chǎn)品品牌 BIOVISION, INC.
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameOrnithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric)
    DescriptionOrnithine decarboxylase (ODC) (EC 3.5.3.1) is a pyridoxal phosphate-dependent enzyme, which cleaves ornithine into putrescine and carbon dioxide. ODC is the initial step in the polyamine synthesis pathway. Putrescine, along with the subsequent polyamine products, spermidine and spermine has been shown to promote cell proliferation and arrest cell apoptosis in cancer. It is also known that proto-oncogenes, such as c-Myc can transcriptionally regulate this protein. Ornithine decarboxylase inhibitors, e.g. efluornithine (2-difluromethylornithine), alexidine and their analogs have been studied as ornithine and employed to irreversibly inhibit ODC and thus abolish cell growth by reducing intracellular polyamine that is required for the aforement
    Size100 assays
    Concentrationn/a
    ApplicationsScreening for inhibitors of human Ornithine decarboxylase I (ODC1)
    Other NamesODC,ornithine decarboxylase
    Gene, Accession, CAS #n/a
    Catalog #K176-100
    Price
    Order / More InfoOrnithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric) from BIOVISION, INC.
    Product Specific Referencesn/a
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