A tropic hormone and agonist of GNRHR (Ki = 13 nM in CHO cells expressing the human receptor); stimulates LH and FSH release from rat anterior pituitary cultures (0.1 μg); stimulates LH release from bovine anterior pituitary cultures (1 μM); induces ovulation in rats pretreated with fluphenazine (ED50 = 610.3 ng/kg)