LSM10, Recombinant, Human, aa1-123, His-SUMO-Tag (U7 snRNA-associated Sm-like Protein LSm10)
Description
Purity ~90% (SDS-PAGE). Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. Source: Recombinant protein corresponding to aa1-123 from human LSM10, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~30.1kD AA