產(chǎn)品名稱 AZD 5582 dihydrochloride from TOCRIS BIOSCIENCE
    產(chǎn)品貨號 5141/50
    產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
    產(chǎn)品規(guī)格 50 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameAZD 5582 dihydrochloride
    DescriptionDimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice. Purity 97%. MW (observed): 1088.21
    Size50 mg
    Concentrationn/a
    Applicationsn/a
    Other Names3,3'-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolinamide
    Gene, Accession, CAS #n/a
    Catalog #5141/50
    Price
    Order / More InfoAZD 5582 dihydrochloride from TOCRIS BIOSCIENCE
    Product Specific Referencesn/a
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