Serum paraoxonase/arylesterase 1 (PON1) also known as aromatic esterase 1 or serum aryldialkylphosphatase 1 is an enzyme that in humans is encoded by the PON1 gene. The PON gene was mapped to chromosome 7q21-q22, and the mouse Pon1 gene was mapped to the proximal end of chromosome 6. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1(paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein(HDL). Sample Type: Cell culture supernates, cell lysates, serum, plasma (heparin) and tissue homogenates Intended Use: For quantitative detection of human PON1 in cell culture supernates, cell lysates, serum, plasma (heparin) and tissue homogenates. Sensitivity: <10pg/ml Range: 31.2-2000pg/ml Specificity: Natural and recombinant human PON1 Test Principle: This human PON1 BioAssay? ELISA Kit was based on standard sandwich enzyme-linked immune-sorb