產(chǎn)品名稱 Dorsomorphin dihydrochloride from TOCRIS BIOSCIENCE
    產(chǎn)品貨號 3093/10
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
    產(chǎn)品規(guī)格 10 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameDorsomorphin dihydrochloride
    DescriptionPotent inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM). Displays no significant activity on several structurally related kinases including ZAPK, SYK, PKCθ, PKA and JAK3. Inhibits AMPK activation induced by AICAR (Cat. No. 2840) and metformin (Cat. No. 2864). Also inhibits bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). Promotes cardiomyogenesis in mouse embryonic stem cells (ESCs) in vitro. Shown to induce autophagy in cancer cell lines via a mechanism independent of AMPK inhibition. Purity 98%. MW (observed): 472.41
    Size10 mg
    Concentrationn/a
    Applicationsn/a
    Other Names6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride. Compound C, BML-275
    Gene, Accession, CAS #CAS: 1219168-18-9
    Catalog #3093/10
    Price
    Order / More InfoDorsomorphin dihydrochloride from TOCRIS BIOSCIENCE
    Product Specific ReferencesPubMed: 20548307, 21715426, 21896918, 21958075, 21982708, 22306606, 22968320, 22972918, 23076030, 23154389, 23362023, 23507034, 23533608, 23555697, 23563587, 23616923, 23754277, 24216509, 24291815, 24308972, 24497921, 25080434, 25286122, 25514175, 25605781, 25622260, 25654758, 25693565, 25822089, 26029847, 26136155, 26136928, 26174015, 26272509, 26539519, 26541394, 26801615, 27320041, 27378374, 27396242, 27428650, 28039410, 28613987, 29396410
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