| 產(chǎn)品詳情 |
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| Product Name | SB 203580 |
| Description | Selective inhibitor of p38 MAPK (IC50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively). Displays 100-500-fold selectivity over LCK, GSK-3β and PKBα. Shown to inhibit IL-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase. Enhances clonal growth of skin epithelial progenitor cells; stimulates neural stem cell (NSC) proliferation. Essential component of medium for maintaining stem cells in naive pluripotent state. Available as part of the MAPK Cascade Inhibitor Tocriset? and MAPK Inhibitor Tocriset?. Water-soluble Salt also available.. Purity 98%. MW (observed): 377.44 |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine |
| Gene, Accession, CAS # | CAS: 152121-47-6 |
| Catalog # | 1202/1 |
| Price | |
| Order / More Info | SB 203580 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 15152046, 15640157, 15659527, 16341839, 16397234, 16627622, 16672661, 17018141, 17145782, 17283097, 17714751, 18053155, 18258605, 18768402, 18815127, 18830681, 19371341, 19523197, 19723763, 19828633, 19887380, 20429916, 20631885, 20852130, 21440539, 21622856, 21642622, 21685895, 21738764, 21854542, 21904110, 21994479, 21995440, 22031657, 22057273, 22220695, 22275752, 22313861, 22328515, 22347375, 22432027, 22451267, 22848503, 23123784, 23315073, 23332156, 23536313, 23693126, 23748100, 23754277, 23967228, 24145351, 24152992, 24172903, 24222778, 24227191, 24280371, 24358263, 24531379, 24558305, 24627558, 24684682, 24736410, 25052197, 25214013, 25243776, 25260613, 25274725, 25398056, 25435694, 25582338, 25712213, 25878490, 25905635, 25936372, 25948586, 25999956, 26065826, 26116509, 26247711, 26251761, 26330750, 27150562, 27520483, 27802323, 28322749, 28442401, 30359318, 30797029 |
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