Inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. Decreases cellular proliferation in human muscular sarcoma cell lines. Also inhibits ErbB2 and VEGFR-2 (IC50 values are approximately 1 μM for both). Purity 99%. MW (observed): 316.46
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
(2E)-3-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2-propenethioamide. Tyrphostin AG 879