Purity >98%. BRL 37344 is a selective agonist of Beta3 -adrenergic receptors with Ki values of 0.43, 9.17, and 37.9 μM for Beta3, Beta2, and Beta1, respectively. Beta3 -Adrenoceptors are expressed in adipose tissue as well as endothelial and myocardial tissues. This compound has been used to explore the role of these receptors in the regulation of thermogenesis and lipolysis and to modulate cardiac function in models of cardiovascular disease. It has also been used in rodents to study the role that Beta3 -adrenergic receptors play in regulating anxiety-like behaviors.