Purity ~90% (SDS-PAGE). May play a role in the integrity of hidesmosome and the attachment of basal keratinocytes to the underlying basent membrane. The 120kD linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies. Source: Recombinant protein corresponding to aa1253-1497 from human COL17A1, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~28.5kD AA