Purity ~90% (SDS-PAGE). COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Source: Recombinant protein corresponding to aa1578-1754 from human COL18A1, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~21.3kD AA