Purity ~98% (HPLC). Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal, lysosomal and vacuolar acidification. Inhibitor of autophagic degradation by rising pH and thus inactivating the lysosomal acid hydrolases. Neuroprotective. Source: Streptomyces griseus Formula: C35H58O9 Solubility: DMSO, 100% ethanol or methanol Molecular Weight: ~622.8