HSP90AB1, Recombinant, Human, aa2-724, His-Tag (Heat Shock Protein HSP 90-beta)
Description
Purity ~90% (SDS-PAGE). Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Source: Recombinant protein corresponding to aa2-724 from human HSP90AB1, fused to His-Tag at N-terminal and Myc-Tag at C-terminal, expressed in E. coli. Molecular Weight: ~88.1kD AA