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Description
Aldolase (fructose bisphosphate aldolase), a glycolytic enzyme, catalyzes the conversion of fructose 1, 6-bisphosphate to 3-phosphoglyceraldehyde. This ubiquitous enzyme is present as three different isozymes: aldolase A, aldolase B, and aldolase C. Studies suggest the potential diagnostic value of quantitative analysis of aldolase A for hepatocarcinoma. Furthermore, the change in aldolase B gene expression levels has also been observed in certain patients with this primary tumor.Synonyms: ALDOA, ALDA, MGC10942, MGC17716, MGC17767