Cyclophilin D is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins and thus their formation. Cyclophilin D is also a mitochondrial matrix protein, which plays a decisive role in mitochondrial permeability transition. It can bind to the immunosuppressant cyclosporine A and its overexpression suppresses the apoptosis in cancer cells. MW: 42.9 kDa. Purity ≥95%