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Description
JMJD2B(Thr305) Polyclonal Antibody. ? Target Background: JMJD2B is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure; the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereb
Immunogen
KLH conjugated synthetic phosphopeptide derived from human JMJD2B around the phosphorylation site of Thr305