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Description
EAR2 Polyclonal Antibody. NR2F6, also known as Nuclear receptor subfamily 2 group F member 6, is a nuclear protein belonging to the nuclear hormone receptor family and NR2 subfamily with a nuclear receptor DNA-binding domain. NR2F6 is a nuclear receptor involved in action regulation of the transcription of the GNRH1 gene. It binds to the TGACCT repeat motif enhancing the renin gene and thus acting as a negative modulator of renin gene transcription. NR2F6 is required early in the development of the locus ceruleus (LC), thus in some way contributing to the regulation of the forebrain clock, at least in part, through targeted release of noradrenalin into the cortical area.
Immunogen
n/a
Other Names
EAR-2, EAR2, ERBAL2, ERBA-related gene-2, V-erbA-related protein 2, nuclear receptor V-erbA-related, nuclear receptor subfamily 2 group F member 6, v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2