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Description
c-Kit(Tyr721) Polyclonal Antibody, Cy5.5 Conjugated. ? Target Background: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory
Immunogen
KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr721. Immunogen Range: 700-750/976