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Description
NATL/LAB Antibody. Non-T cell Activation Linker (NTAL) is also known as linker for activation of B cells (LAB), is a transmembrane adaptor protein. NTAL is expressed in B cells, mast cells, monocytes and NK cells. When NTAL is tyrosine phosphorylated, it recruits signalling molecules such as Grb2, Gab2 and c-Cbl into receptor-signalling complexes. Mutation in the NTAL gene may cause Williams-Beuren syndrome, a rare genetic disorder.
Immunogen
Synthetic peptide surrounding amino acid 187 of rat NTAL