Recombinant Human NEDD8-conjugating enzyme UBE2F (UBE2F)
Description
Purity > 90% as determined by SDS-PAGE. MW: 48.1kDa. Full Length: 1-185aa. N-terminal GST-tagged. Homo sapiens (Human). Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2; Ubiquitin-conjugating enzyme E2 F