If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
IGF1R (pY1161) Antibody is a Rabbit Polyclonal antibody against IGF1R (pY1161). This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
Immunogen
Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y1161 of human IGF1R.