Macrophage Colony-Stimulating Factor (CSF1) (AA 1-149) protein
Description
Macrophage Colony Stimulating Factor M-CSF, also known as CSF-1, is a four alpha helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. M-CSF is also essential for the survival and proliferation of osteoclast progenitors. M-CSF also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.