A fungal metabolite; suppresses the expression of COX-2 and iNOS and inhibits production of nitric oxide and PGE2 in LPS-stimulated RAW 264.7 and BV2 cells; inhibits NF-κB DNA-binding activity, nuclear translocation of NF-κB p65 and p50 heterodimers, and blocks degradation IκBα in the cytoplasm of LPS-stimulated RAW 264.7 and BV2 cells; inhibits the growth of F. graminearum; inhibits PTB1B in vitro (IC50 = 64 μM)