Prolactin protein.Prolactin is a lactogenic hormone secreted by the adenohypophysis. Besides its major action on lactation, insome species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation, andosmoregulation. Prolactin has been shown also to havecytokine-like and important immunoregulatory activities. Itcontributes to the development of lymphoid tissues and themaintenance of physiological immune function and alsomodulates a variety of T-cell immune responses. Prolactinhas been reported to activate cellular proliferation in nonreproductive tissue, such as liver, spleen, and thymus. Itinduces significant proliferation in aortic smooth musclecells and also enhances proliferation of these cells inducedby PDGF. Prolactin also appears to be directly mitogenicfor pancreatic beta cells. Prolactin is also mitogenic forcultured astrocytes.Recombinant Ovine Prolactin produced in E. coli is a single, non-glycosylated polypeptide chain containing 200amino acids and having a molecular mass of 23 kDa.Recombinant ovine Prolactin is purified by proprietarychromatographic techniques. MW: 23 kDa. Purity > 95% pure by SDS-PAGE and RP-HPLC