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Description
PE anti-human CD213a2 (IL13Rα2). CD213a2, also known as IL13Rα2, is a type I transmembrane protein and member of the hematopoietin family. IL13Rα2 is the high affinity receptor for IL-13, but it possibly acts as a decoy receptor to antagonize IL-13Rα1/IL-4Ra-mediated IL-13 biological functions. IL13Rα2 is expressed by fibroblasts, smooth muscle cells, keratinocytes, and activated B cells. However, its presence on the cell surface is highly regulated. CD213a2 is also expressed in various types of cancer which makes it an attractive therapeutic target.