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| Antigenic Specificity | MNAR |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:20-1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MNAR Polyclonal Antibody. Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence- specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1. May have important functional implications in ER/growth factor cross-talk. Interacts with several growth factor signaling components including EGFR and HRS. Involved in nuclear receptor signaling via its interaction with AR and NR3C1. |
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| Immunogen | n/a |
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| Other Names | HMX3, MNAR, P160, modulator of non-genomic activity of estrogen receptor; modulator of nongenomic activity of estrogen receptor; proline and glutamic acid rich nuclear protein; proline, glutamic acid and leucine rich protein 1; proline-, glutamic acid- and leucine-rich protein 1; proline-, glutamic acid-, leucine-rich protein 1; transcription factor HMX3 |
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| Gene, Accession # | Entrez: 27043; Uniprot: Q8IZL8 |
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| Catalog # | PA5-63893 |
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| Price | |
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| Order / More Info | MNAR Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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