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Description
Mouse Anti-CHEK1 Recombinant Antibody (CBXC-2763). This product is a mouse antibody that recognizes CHEK1. The antibody CBXC-2763 can be used for immunoassay techniques such as: WB. The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcrip