α7 nicotinic acetylcholine receptor (nAChR) agonist (EC50 = 1.6 μM, Ki = 260 nM at rat α7 nAChRs). Also displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs (IC50 = 8.5 μM). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. Brain penetrant and orally bioavailable. Purity 99%. MW (observed): 339.43
Size
50 mg
Concentration
n/a
Applications
n/a
Other Names
N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide. WAY 317538