An orally bioavailable activator of Nurr1; selective for Nurr1 over Nur77, Nor1, and RXR; inhibits proliferation of Ku7 and 253J B-V bladder cancer cells in a dose-dependent manner at concentrations ranging from 2.5-10 μM; suppresses bladder cancer cell growth by 44 and 59% at doses of 12.5 and 25 mg/kg, respectively; neuroprotective in an MPTP mouse model of Parkinson's disease; has analgesic and anti-inflammatory activity at a dose of 100 mg/kg in rats