Purity ~90% (SDS-PAGE). Appears to regulate cell growth through interactions with the Extracellular domain matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity. Source: Recombinant protein corresponding to aa18-303 from human SPARC, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~59.7kD AA
Size
10ug, 50ug, 100ug
Concentration
n/a
Applications
n/a
Other Names
Basement-membrane protein 40, BM-40 Osteonectin, ON Secreted protein acidic and rich in cysteine