If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. Synonyms: Polyclonal MAGEL2 antibody, Anti-MAGEL2 antibody, MAGE-like 2 antibody, NDNL1 antibody, nM15 antibody.
Immunogen
MAGEL2 antibody was raised in rabbit using the C terminal of MAGEL2 as the immunogen