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Description
Creatine kinase (CK) is a major enzyme involved in energy metabolism in tissues with large fluctuations of energetic demand. CK catalyses the reversible transfer of a high energy phosphoryl group between ATP and phosphocreatine. Creatine kinase consists of B subunit (brain type) and M subunit (muscle type) and therefore three different cytosolic isoenzymes exist: CK-MM, CK-BB and CK-MB. The major muscle isoform, CK-MM, is a homodimer of the M subunit. In contrast to muscle, the major creatine kinase isoform in brain is BB creatine kinase. In a few tissues, especially myocardium, a heterodimeric isoform MB creatine kinase is present.Rabbit Anti-Creatine kinase B Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 100-150 of human Creatine kinase B (Swiss Prot: P12277).
Immunogen
KLH-coupled synthetic peptide within AA 100-150 of human Creatine kinase B